28 August - 2 September 2016 Invited Session at HEC 2016 (Health - Exploring Complexity: an Interdisciplinary Systems Approach), Munich, Germany

August 25th 2016 Mini-Symposium at ISCB (International Society for Clinical Biostatistics) in Birmingham, UK

July 10-15, 2016 Invited Session at the 28th International Biometric Conference, Victoria, Canada

  • Title: "Methodological challenges in observational studies - current perspectives and future directions in functional form, measurement error and causal inference"
  • Organizer: James Carpenter

July 3-8, 2016 1st General Meeting of the STRATOS members at the Banff International Research Station (BIRS), Banff, Canada.

  • Title: "Developing a Comprehensive, Integrated Framework for Advanced Statistical Analyses of Observational Studies"
  • Official BIRS report - PDF



Wednesday August 26, 2015 Invited Session at ISCB 2015, Utrecht, The Netherlands (Abstracts STRATOS).

1) Scientific session 9.00-11.00

Katherine Lee, Melbourne, AUS Regression modelling with missing data: principles, methods, software and examples PDF

Stephen Evans, London, UK STRengthening Analytical Thinking for Observational Studies: the STRATOS initiative: study design PDF

Aris Perperoglou, Essex, UK Multivariable regression modelling using splines. A review of available packages in R  PDF

Terry Therneau, Minnesota, US The STRATOS survival task group PDF

2) During the lunchbreak on Wednesday

12.35 - 13.15 General information, public meeting 13.15 - 13.55 Closed meeting, for members only



Wednesday, 27th August 2014 ISCB2014 in Vienna

STRATOS had a scientific session and a session discussing future steps (Abstracts STRATOS).

1) Scientific session 9.00-11.00

STRATOS (Strengthening Thinking about Analyses of Observational Studies) initiative: first results & future steps

Organizers: Willi Sauerbrei, D, and Harbajan Chadha‐Boreham, CH

Willi Sauerbrei, Freiburg, D Introduction PDF

Marianne Huebner, East Lansing, USA Setting the stage with initial data analyses Video (includes Introduction by Willi Sauerbrei) PDF

Ewout Steyerberg, Rotterdam, NL Evaluation of incremental value of a marker: a historic perspective on the Net Reclassification Improvement Video PDF

Michal Abrahamowicz, Montreal, CAN Review of methods used in recent observational epidemiological studies to select variables and their functional forms (STRATOS Task Group 2) Video PDF

Els Goetghebeur, Gent, B Causal questions and principled answers: a guide through the landscape for practicing statisticians Video PDF

2) During the lunchbreak on Wednesday

12.35 - 13.15 General information, public meeting 13.15 - 13.55 Closed meeting, for members only
First publication: Sauerbrei W, Abrahamowicz M, Altman DG, le Cessie S and Carpenter J on behalf of of STRATOS initiative. STRengthening Analytical Thinking for Observational Studies: The STRATOS initiative. Statistics in Medicine, 2014.



The STRATOS initative was launched at a half-day Mini-Symposium on the last day of the ISCB meeting in Munich, in August 2013. Abstracts-STRATOS
There were three general talks by Willi Sauerbrei PDF, Doug Altman PDF and James Carpenter PDF. James also introduced a route map by using TG1 (missing data) as an example.
In addition, there were specific talks discussing key issues of TG2 through TG7:
  • TG2 Selection of variables and functional form, Michal Abrahamowicz PDF
  • TG3 Descriptive and initial data analysis, Saskia Le Cessie PDF
  • TG4 Measurement error, Helmut Küchenhoff PDF
  • TG5 Design, Doug Altman PDF
  • TG6 Evaluating diagnostic tests and prediction models, Petra Macaskill PDF
  • TG7 Causal Inference, Els Goetghebeur PDF